PAIN+ CPN

Rejas-Fernandez A, de-la-Llave-Rincon AI, Romero-Morales C, et al. Ultrasound-guided application of percutaneous electrolysis as an adjunct to exercise and manual therapy for tibialis posterior tendinopathy: A randomized clinical trial. J Pain. 2026 Feb 20;42:106236. doi: 10.1016/j.jpain.2026.106236. (Original study)
Abstract

Percutaneous electrolysis has been advocated as a therapeutic strategy for tendinopathies; however, no previous trials have investigated the effects of percutaneous electrolysis on the treatment of tibialis posterior tendinopathy. The aim of this study was to investigate the effects on pain and disability of adding percutaneous electrolysis to a manual therapy and exercise program in individuals with tibialis posterior tendinopathy. A randomized clinical trial (clinical registry: NCT05370092) was conducted. Forty-six (n=46) patients with tibialis posterior tendinopathy were randomized into manual therapy/exercise (n=23) or manual therapy/exercise and percutaneous electrolysis (n=23) group. All participants received the same manual therapy/exercise protocol (one session/week, 4 weeks). Those allocated to electrolysis group also received this intervention US-guided at each treatment session. Pain intensity (Numerical Pain Rate Scale) as primary outcome and disability as secondary outcome (Foot and Ankle Ability Measure, FAAM) were assessed at baseline, post-treatment and at 3- and 6- months. Patients receiving percutaneous electrolysis had significantly greater improvements in pain (post: ?-3.4, 95%CI -4.8 to -2.0; 3months: ?-3.4, -5.0 to -1.8; 6months: ?-2.6, -4.2 to -1.0) and disability (post: FAAM/Sports ?49.6, 95%CI 34.6-64.6 - FAAM/ADL ?26.9, 14.6-39.2; 3months: FAAM/Sports ?31.6, 14.8-48.4 - FAAM/ADL ?4.9, 2.0-7.8; 6months: FAAM/Sports ?17.4, 2.0-32.8 - FAAM/ADL ?2.4, 1.0-3.8) than those receiving just manual therapy/exercise alone. This clinical trial found that adding US-guided percutaneous electrolysis to a manual therapy/exercise program was more effective for improving pain and disability than the application of just manual therapy/exercise in people with tibialis posterior tendinopathy at short-term and mid-term follow-ups. LEVEL OF EVIDENCE: Therapy, Level 1b PERSPECTIVE: This clinical trial found that adding US-guided percutaneous electrolysis to a manual therapy/exercise program was more effective for improving pain intensity and disability than the application of manual therapy/exercise alone in subjects with tibialis posterior tendinopathy at short-term and mid-term follow-ups.

Ratings
Discipline Area Score
Physician 5 / 7
Comments from PAIN+ CPN subscribers

No subscriber has commented on this article yet.