PAIN+ CPN

Can G, das Virgens IPA, Feher B, et al. Physiotherapy for endometriosis-associated pelvic pain: a systematic review and meta-analysis. Pain Med. 2026 Jan 1;27(1):95-103. doi: 10.1093/pm/pnaf083. (Systematic review)
Abstract

IMPORTANCE: Endometriosis is a disease often associated with chronic pelvic pain. It affects around 190 million females of reproductive age globally.

OBJECTIVE: To investigate the effect of physiotherapy techniques (PTs) in relieving endometriosis-associated pain.

DESIGN: This systematic review and meta-analysis followed the PRISMA 2020 and Cochrane Handbook guidelines. The study protocol was followed and registered on PROSPERO (CRD42023474231).

SETTING: A systematic search was conducted in 3 databases: PubMed, Embase, and Cochrane.

PARTICIPANTS: We used the following PICO strategy: population, women with endometriosis-associated pelvic pain; intervention, PTs; comparator, non-PTs; outcome, pelvic pain changes. The article selection was conducted by 2 independent reviewers.

MAIN OUTCOME(S) AND MEASURE(S): Two authors extracted data independently from the eligible articles. For continuous outcomes, the mean difference (MD) in change scores between intervention and control groups was used as an effect size with a 95% confidence interval (CI). Within-group correlation of before- and after-treatment was assumed to be equal across groups and studies.

RESULTS: Out of 8 eligible studies identified in our selection, 7 were included in the quantitative analysis. PTs were effective in reducing pain compared to non-PTs (MD -1.97, CI -2.99 to -0.95), and physiotherapy modalities (electrotherapy and laser devices) had the greatest reduction in pain levels (MD -2.03, CI -3.9 to -0.14) among all studies. Additionally, locally applied techniques resulted in greater pain reduction than the generally applied techniques.

CONCLUSION AND RELEVANCE: Physiotherapy techniques are effective in reducing pain in women with endometriosis, especially when applied locally.

Ratings
Discipline Area Score
Physician 6 / 7
Rehab Clinician (OT/PT) 5 / 7
Comments from MORE raters

Physician rater

Well-implemented systematic review and meta-analysis with a beneficial conclusion for women. In such a complex clinical condition, it is very important to have non-pharmacological alternatives that help reduce pain.
Comments from PAIN+ CPN subscribers

No subscriber has commented on this article yet.